The computer giant will be working with its 1500 Scottish partner companies to take on 2016 16-24-year-old IT apprentices over the next three years.
Microsoft UK Managing Director, Michel Van der Bel, announced the company's plans while meeting with Scotland's First Minister Alex Salmond.
Mr Van der Bel said: "The digital technologies industry employs over 100,000 people in Scotland and is expanding fast. At Microsoft we want to help ensure there are skilled people coming into the workplace to secure the future for the sector.
"That's why we are announcing our commitment to create 2,016 apprenticeships in Scotland by 2016 by partnering with the Scottish Government and our training providers QA and YouTrain.
"These are real jobs for young people in a vibrant, growing and exciting industry, which will help bring economic and employment opportunities."
Mr Salmond called the announcement a "huge endorsement" for young people in Scotland, saying: "This is a terrific announcement both for the thousands of individual young people who will be given a fantastic career opportunity and for Scotland's Modern Apprenticeship programme.
"Over the next three years Microsoft and its partner companies will recruit 2,016 young people, give them real jobs and train them so that they are equipped with the skills and expertise to work in the IT industry.
"Microsoft is supporting investment in Scottish skills and in its own future in Scotland. Recruiting 2,016 apprentices by 2016 represents a huge endorsement of Scotland's young people from a company with operations in dozens of countries."
Scotland's Youth Employment Minister Angela Constance calls Microsoft's plan "another sign of the enormous value of the apprenticeship scheme to companies and individuals", adding: "The Scottish Government is committed to at least 25,000 MAs in each year of this Parliament and has guaranteed a place in training or education for every 16 to 19-year-old through Opportunities for All.
"The partnership of companies like Microsoft is key to this work which will support more young people into jobs."